Assistant Professor, Department of Chemistry, Guru Ghashidas University, Bilaspur, India

Speech Title: Nanostructured Chiral (salen)Co Catalyst Bearing Lewis acid: Application in Asymmetric Ring Opening Reactions of Terminal Epoxides
Abstract: The homogeneous chiral salen Co(III) catalyst bearing Lewis acid has been covalently tethered to an inorganic solid support mesoporous material to design and develop heterogeneous nanostructured chiral catalyst. The nanostructured chiral salen cobalt catalyst proved to be important for the preparation of valuable chiral intermidiates i. e. optically active terminal epoxides and diols via the hydrolytic kinetic resolution route of racemic terminal epoxides. The confined nanospaces of mesoporous inorganic porous supports offer an improved activity and enantioselectivity of asymmetric catalytic reactions. Further, the potential benefits of heterogenization include facilitation of catalyst separation from reagents and reaction products, simplification of methods for catalyst recycle reusability and possible adaptation of immobilized catalyst to continuous-flow process.
Keywords: Nanostructured chiral catalyst, Asymmetric reaction, Terminal epoxides, Hydrolytic Kinetic Resolution